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Both the high and low dose of FST-344 given to the subjects elicited an increase in circulating follistatin levels, however, the high dose resulted in a 15.3 +/- 2.1 ng/ml increase in follistatin serum levels while the low dose only increased levels by 6.8 +/- 0.4 ng/ml

It is reasonable to conclude that SalB may be a pleiotropic molecule exerting anti-fibrotic effects against numerous signaling cascades after carefully reviewing the studies on SalB s effects on fibrosis