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Proceedings of the National Academy of Sciences

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Unlike some medications that require multiple daily doses, semaglutide is a once-weekly injection designed to maintain stable hormone levels that trigger fullness and reduce hunger signals

The primary effects of GLP-1 RA involve controlling blood glucose levels in individuals with T2DM by promoting glucose-dependent insulin release [67], inhibiting glucagon production, decreasing hepatic glucose output [68], improving insulin secretion, reducing the apoptosis of -cells, promoting the proliferation of -cells [69] and curbing weight gain [70]