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Nutritional Strategy (Not Restriction) In perimenopause, the focus shifts from calorie counting to metabolic support: Protein prioritization: 1.2-1.6g per kg body weight to preserve muscle mass Metabolic flexibility: Teaching your body to efficiently use both carbohydrates and fats Nutrient timing: Aligning eating patterns with hormone rhythms and activity Anti-inflammatory eating: Reducing foods that promote insulin resistance and inflammation Strategic supplementation: Magnesium, vitamin D, omega-3s, berberine for metabolic support This isnt about deprivationits about providing your body with what it needs to function optimally during a metabolic transition

Glucose-dependent Insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 Module via a Cyclic AMP/cAMP-dependent Protein Kinase/Rap1-mediated Pathway