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Overall, ITP-LNP/siBACE1 was more effective at improving behavioral and AD-like pathological features in APP/PS1 mice than compared with the other treatment conditions, reflecting the potential of allosteric targeting for the treatment of disorders associated with deletion of the ectodomain of the target receptor

Kubes P, Mehal WZ

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Other well-established risk factors for vulvovaginal candidiasis, according to the British Association for Sexual Health and HIV (BASHH) guidelines, include recent antibiotic use, pregnancy, immunosuppression (including high-dose corticosteroids), and certain contraceptives