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Neurological symptoms associated with B12 deficiencysuch as paraesthesia, ataxia, or cognitive impairmentrequire urgent treatment with more frequent injections (1mg on alternate days initially) to prevent irreversible nerve damage

According to certain studies, the markers of worsened OxS in patients with Hashimoto thyroiditis were closely related to the levels of TG or TPO antibodies (9799)

FDA banned it in late 2023 "Category 2: Substance with Safety Concerns" Why the FDA banned it: Potential immune reactions (immunogenicity) Manufacturing impurities in compounded versions Complete lack of human safety data Risk of contamination Legal status: NOT FDA-approved Illegal to compound in pharmacies Banned by WADA for athletes Possession not illegal (it's not a DEA scheduled substance) Sold online as "research chemical" 2

Consistent with our Ki67 results we also see increased BrdU-ir cells at 2 hours in males compared with females, but no differences at 24 hours, which likely has to do with the population that Ki67 labels versus the pulsatile BrdU (Kee et al., 2002)