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Another mechanism by which CBD induces apoptosis is increasing the expression of death receptor-5 (DR5), to which TNF-Related Apoptosis-Inducing Ligand (TRAIL) binds and stimulates apoptosis in colorectal cancer cells, which in return increases the sensitivity to TRAIL leading to increased apoptosis in CRC, but it didnt affect the normal colorectal cells

Hashish is the compressed resin extracted from the heads, and cannabis oil is extracted from it by dissolving it in alcohol