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Dimensions: 3664 x 2442 px | 31 x 20.7 cm | 12.2 x 8.1 inches | 300dpi Date taken: 10 March 2019

Single-cell RNA sequencing studies in murine smoke models have identified an excessive influx of monocyte-derived macrophage subset population responsible for heightened inflammation and ECM remodeling, a finding that has also been validated in emphysematous COPD patients 59

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