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Our results confirm the notion that cEDS is basically characterized by cutaneous and articular involvement, even though none of their hallmarks is represented in 100% of cases, and show that osteoarticular and musculoskeletal complaints as well as gastrointestinal, uro-gynecological, neuropsychiatric, and cardiovascular associated symptoms (and disorders) are not so prominent compared to other EDS subtypes

Siegmund from the USC Norris Comprehensive Cancer Center and the Department of Population and Public Health Sciences, Keck School of Medicine of USC, University of Southern California