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This includes research that links inhaling the heated tobacco vapour of an e-cigarette to an increased risk of developing asthma and chronic obstructive pulmonary disease

The addictive properties of tobacco primarily stem from nicotine, which rapidly reaches the brain upon inhalation or absorption through the mucous membranes, according to an article by the Food and Drug Administration 2024, titled Nicotine Is Why Tobacco Products Are Addictive Once in the brain, nicotine binds to nicotinic acetylcholine receptors, stimulating the release of neurotransmitters, including dopamine, which creates pleasurable sensations and reinforces the behavior of tobacco use

It is difficult to make clinical recommendations in this setting

Salvi Ge, Lawrence H P, Offenbacher S, Beck J D