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Factors such as genetics, environment, and individual susceptibility can also contribute to the development of nicotine addiction

Carbon Monoxide enters the blood from the lungs and combines with hemoglobin, blocking the bloods ability to carry oxygen to body cells

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But, either way, it supports the fact that inhalation of any substance that has carcinogens and tar in it is going to lead to airway inflammation and premature development of some emphysema. Rizzo said researchers face other problems with studying marijuana users