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The higher temperature of cannabis smoke can affect lung function tests by causing greater irritation and inflammation in the large airways, potentially leading to uncomfortable symptoms like chest tightness, shortness of breath, and altered lung function, as shown in numerous studies, including American Lung Association findings

Smoking and mental illness: a population-based prevalence study

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Participants randomly received an e-cigarette that delivered 36, 8 or 0 mg/mL of nicotine, or a cigarette substitute that contained no tobacco, as an aid in their efforts to reduce their cigarette consumption