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[DOI] [PMC free article] [PubMed] [Google Scholar] 85.Kosmider L, Sobczak A, Prokopowicz A, Kurek J, Zaciera M, Knysak J, et al

Furthermore, the authors proposed a mechanism-of-action, whereby 2 -agonists stimulate adenylyl cyclase, leading to cyclic AMP accumulation, activation of protein kinase G, and opening of large conductance calcium-activated potassium (BK Ca ) channels, thereby inhibiting sensory nerve depolarisation

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The decline in ammonium concentration was complemented by an increase in nitrate-N concentration during the same period (Figure 6-2), indicating ammonium conversion to nitrate