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Research clearly demonstrates that smoking increases a patients risk for cancer, but if the smoking status of a patient is reported at all, it is often downcoded to uncomplicated. This may be the result of the uncomplicated code being first in the drop-down box, but is more often the result of incomplete documentation within the providers progress notes

Only about half of the people diagnosed with mouth or throat cancer survive more than 5 years

Disruption of endoplasmic reticulum function can lead to the accumulation of misfolded proteins, endoplasmic reticulum stress, and activation of the unfolded protein response (UPR)

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