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What is so exciting about our study is that it shows that its never too late to quit some of the people in our study had smoked more than 15,000 packs of cigarettes over their life, but within a few years of quitting many of the cells lining their airways showed no evidence of damage from tobacco. Smoking causes up to 10,000 extra mutations in nine out of every 10 lung cells, the researchers found, including many that cause cancer

Tobacco advertising, promotion and sponsorship are banned in Canada and warnings on cigarette packs have existed since 1972

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They were randomly assigned to smoke cigarettes with the usual amount of nicotine or those that had nicotine content reduced in stages over 18 weeks