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To accomplish this is the object of the machine under consideration, which is so constructed as to imitate the motions of a smoker, who, at regular intervals, would inhale a definite volume of air with a definite and constant force of suction.I am omitting the middle of the article because it focuses on the mechanics of Parenty's Smoking Machine, but if you are interested you can find it in issue 54 of Scientific American (23 January 1886)

However, such a treatment is years away from being tested in people, according to NIDA

It defines you. There are few places where complete strangers can meet in the spirit of friendship

No Sense of Humor: Part of his schtick was to play dumb whenever someone told him a joke, claiming that he had no idea what the other person was talking about