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Nicotine also disrupts lipid metabolism, raising low-density lipoprotein (LDL) and triglyceride levels while lowering high-density lipoprotein (HDL)

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Earlier observations of Pryor and his associates (8) suggested that the principal relatively stable radical in cigarette tar might be quinone/hydroquinone/semiquinone complex which was an active redox system and that this redox system was capable of reducing molecular oxygen to produce superoxide, leading to hydrogen peroxide and hydroxyl radicals, which may eventually lead to oxidative damage of biological macromolecules

FDA to regulate e-cigarettes, ban sales to minors