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Analysis of the lipid partitioning characteristics of salmeterol indicate that it orients itself within the lipid bilayer in a configuration that facilitates its entering the receptor's active site by lateral movement through the bilayer with presentation of its phenyl-alkoxy-alkyl tail as a passkey to an access route located between transmembrane helices 1 and 7 (Szlenk et al, 2021)
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1 /Jan 2021, New York State Department of Health Bureau of Tobacco Control, Bureau of Tobacco Control 3 Hispanic and Latino People Experience a Health Burden from Commercial Tobacco Substance Abuse & Mental Health Data Archive
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