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Smoking cessation may also increase the concentration of other drugs partially metabolized by the CYP1A2 enzyme, such as imipramine, olanzapine, clomipramine, and fluvoxamine, although data are limited and the possible clinical significance is unknown

NICE guidance NG202 [footnote 48] sets out the following recommendations for health and social care workers in primary and community settings

In extreme cases this can be followed by hypotension, a rapid, weak, irregular pulse, breathing difficulty, general weakness, circular, and collapse, finally, convulsions