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The only slight drawbacks are its shorter filter life, overly minimalist controls which necessitate multiple combination hold-and-taps to adjust various features and a display that shuts off only on the lowest fan setting

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As between-study heterogeneity can be underestimated or even zero when the number of studies is small 196,197 , we used Fishers information matrix to estimate the uncertainty of the heterogeneity 198 and incorporated that uncertainty into the final results