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Twenty-three-year-olds should not be out of breath at an exercise intensity equivalent to a moderate walk. We initially collected data on just a few e-cigarette users, as we were doing similar work examining pulmonary blood flow in elderly patients with smoking-induced lung damage, explains Thomas Williams, the graduate student who was first author on the study

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Immune system changes Chemicals in cigarette smoke may stimulate special immune cells known as B cells and T cells and cause them to attack the body, resulting in autoimmune diseases (diseases where the immune system attacks itself)

"A letter came in saying Green Day would like to be on 'The Simpsons' at that day that we were writing the scene," Jean told Movies Online