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Potential harm due to flavor chemicals is further supported by an in vitro study in which maltol increased secretion of IL-8 from BEAS-2B cells and decreased barrier function in human bronchial epithelial cells 30 and by animal studies in which maltol produced long-term adverse health effects in rats and dogs 31 and elicited liver and kidney damage in mice 32

This depends on the brand

I think a lot of the narrative right now is male isolation and loneliness, and theyre dangerous, and theyre lashing out, and theyre crazy

Hilary Whiteman/CNN All wrapped in a betel leaf A woman sells betel leaves at a market in central Yangon