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Common Conditions and Treatments: Smokeless tobacco keratosis: Treatable by reducing or stopping tobacco use Leukoplakia and erythroplakia: Diagnosed with a biopsy Verrucous carcinoma and squamous cell carcinoma: Serious diseases requiring quick treatment that might include extensive surgery, chemotherapy, or radiation Preventing Pathologic Manifestations of Smokeless Tobacco Using smokeless tobacco can potentially lead to various health issues, including those discussed previously

"We were totally unprepared for the finding," Dr Peter Campbell, from the Sanger Institute, told BBC News

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Decisions regarding management should be guided by objective clinical response