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Effect of Volatile Organic Compounds on Intestinal Microbiota Cigarette smoke contains large amounts of toxic volatile organic compounds (VOCs), such as isoprene, acrylonitrile, 1, 3-butadiene, acrylonitrile, styrene and benzene, which are inhaled into respiratory tract and induce different diseases, such as respiratory and cardiovascular diseases, and cancers (Pazo et al., 2016)

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The leading manufacturer, Juul, for example, saw its sales increase nearly sevenfold between 2014 and 2017

Although they are not the same product, the production steps are the same In addition to cigarettes, rolling a joint can be quite challenging for novices