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Highlights: Quitting chewing tobacco for 20 years cuts cancer risk by 40% compared to current users Current tobacco chewers face 21 times higher buccal mucosa cancer risk than never users India records nearly 141,000 new oral cancer cases annually , one-third of global burden Quitting tobacco significantly lowers the risk of buccal mucosa cancer , with long-term cessation cutting the odds by up to 62% compared to current users (1 Trusted Source The impact of tobacco cessation on buccal mucosa cancer risk: A multi-centre case-control study in India Go to source)