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Surgeon General concluded that users of chewing tobacco should know that chewing tobacco "is not a safe substitute for smoking cigarettes." Chewing tobacco contains nicotine, which is highly addictive, as well as several known cancer-causing chemicals

Electronic supplementary material Additional file 1: Table S1: Multinomial logistic regression for perceptions of SLT packaging with graphic or text health warning labels

All these things lead to nicotine dependence and eventually nicotine addiction

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