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As noted by the authors of the study, tobacco "has arguably had the most critical social and economic impact" of all "the intoxicant plants preferred by humans." In an excavation of the Wishbone site in the Great Salt Lake Desert of present-day Utah, lead author Daron Duke and his colleagues found four "charred" seeds from a wild desert variety of tobacco known as Nicotiana attenuata

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The North American market for natural herbal cigarettes was valued at USD 1.2 billion in 2024 and is projected to expand from USD 1.3 billion in 2025 to USD 2.1 billion by 2033, reflecting a CAGR of approximately 6.8% during 2026-203This growth is underpinned by increasing regulatory restrictions on tobacco, rising consumer health awareness, and a burgeoning wellness culture that favors natural alternatives