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Later with prolonged use this area of mucosa changes to more defined conditions referred to as leukoplakia or erythroplakia

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We also tested whether cigarette-only smokers and co-consumers differed on cigarette dependence measures (frequency of smoking, cigarettes smoked per day, perceived addiction to cigarettes, urges to smoke cigarettes), motivation to quit smoking (plans to quit cigarette smoking, attempts to quit smoking cigarettes) and high-risk alcohol consumption by the presence or absence of depressive symptoms