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Cig-a-likes look similar to combustible cigarettes.[7] In addition to nicotine, propylene glycol, and vegetable glycerin, e-liquids contain benzyl alcohol, terpenes, pyrazines, formaldehyde, acetaldehyde, acrolein, and toluene.[8] The inhalational safety of these compounds is unknown.[9] The presence of diacetyl in e-liquids is a concern because it is a known pulmonary toxin and has a propensity for causing bronchiolitis obliterans, also known as popcorn lung.[9] Of particular concern is the addition of vitamin E acetate in tetrahydrocannabinol-containing e-liquids purchased on the black market because it appears to be associated with the recent outbreak of acute e-cigarette, or vaping, product use-associated lung injury (EVALI).[10-12] Further research is necessary to better characterize the inhalational health risks of these compounds

THC is the primary psychoactive compound in cannabis